Detalhe da pesquisa
1.
VSIG4 interaction with heparan sulfates inhibits VSIG4-complement binding.
Glycobiology
; 33(7): 591-604, 2023 08 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37341346
2.
Autoantibodies are associated with disease progression in idiopathic pulmonary fibrosis.
Eur Respir J
; 61(5)2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37080573
3.
IL-4 and IL-13, not eosinophils, drive type 2 airway inflammation, remodeling and lung function decline.
Cytokine
; 162: 156091, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36481478
4.
Targeting immunodominant Bet v 1 epitopes with monoclonal antibodies prevents the birch allergic response.
J Allergy Clin Immunol
; 149(1): 200-211, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34126155
5.
Chronic pharmacological antagonism of the GM-CSF receptor in mice does not replicate the pulmonary alveolar proteinosis phenotype but does alter lung surfactant turnover.
Clin Sci (Lond)
; 135(22): 2559-2573, 2021 11 26.
Artigo
Inglês
| MEDLINE | ID: mdl-34778899
6.
Dual blockade of IL-4 and IL-13 with dupilumab, an IL-4Rα antibody, is required to broadly inhibit type 2 inflammation.
Allergy
; 75(5): 1188-1204, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31838750
7.
IL-33 blockade affects mediators of persistence and exacerbation in a model of chronic airway inflammation.
J Allergy Clin Immunol
; 144(6): 1624-1637.e10, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31562870
8.
Moving toward endotypes in atopic dermatitis: Identification of patient clusters based on serum biomarker analysis.
J Allergy Clin Immunol
; 140(3): 730-737, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28412391
9.
A randomised phase IIb study of mavrilimumab, a novel GM-CSF receptor alpha monoclonal antibody, in the treatment of rheumatoid arthritis.
Ann Rheum Dis
; 76(6): 1020-1030, 2017 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-28213566
10.
Targeting the GM-CSF receptor for the treatment of CNS autoimmunity.
J Autoimmun
; 84: 1-11, 2017 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-28641926
11.
IL-18 associated with lung lymphoid aggregates drives IFNγ production in severe COPD.
Respir Res
; 18(1): 159, 2017 08 22.
Artigo
Inglês
| MEDLINE | ID: mdl-28830544
12.
Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium.
Respir Res
; 18(1): 82, 2017 05 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28468623
13.
An anti-human ICAM-1 antibody inhibits rhinovirus-induced exacerbations of lung inflammation.
PLoS Pathog
; 9(8): e1003520, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23935498
14.
Rituximab causes a polarization of B cells that augments its therapeutic function in NK-cell-mediated antibody-dependent cellular cytotoxicity.
Blood
; 121(23): 4694-702, 2013 Jun 06.
Artigo
Inglês
| MEDLINE | ID: mdl-23613524
15.
Quantitative measurement of the target-mediated internalization kinetics of biopharmaceuticals.
Pharm Res
; 32(1): 286-99, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25208874
16.
Danger-associated molecular patterns and danger signals in idiopathic pulmonary fibrosis.
Am J Respir Cell Mol Biol
; 51(2): 163-8, 2014 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-24749648
17.
Targeting interleukin-13 with tralokinumab attenuates lung fibrosis and epithelial damage in a humanized SCID idiopathic pulmonary fibrosis model.
Am J Respir Cell Mol Biol
; 50(5): 985-94, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24325475
18.
Nonclinical safety of mavrilimumab, an anti-GMCSF receptor alpha monoclonal antibody, in cynomolgus monkeys: relevance for human safety.
Toxicol Appl Pharmacol
; 279(2): 230-9, 2014 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24937321
19.
Development of a mouse model mimicking key aspects of a viral asthma exacerbation.
Clin Sci (Lond)
; 126(8): 567-80, 2014 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-24152048
20.
Serum biomarker profiles suggest that atopic dermatitis is a systemic disease.
J Allergy Clin Immunol
; 141(4): 1523-1526, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29410314